The "check-the-box" compliance era is dead, yet many financial institutions remain trapped in outdated AML frameworks that can't keep pace with real-time threats or emerging technologies like deepfakes and AI-generated financial crime. The future belongs to institutions that can answer one fundamental question at the speed of now: do you truly know who you're doing business with? This panel brings together industry leaders to explore how successful AML transformation requires human-led strategies with robust frameworks first—not technology band-aids. Attendees will discover practical approaches to building perpetual, risk-based AML programs that embed compliance into speed-to-market strategies while remaining auditable and defensible.